Principal Hospital Scientist, Blood and Marrow Transplant Laboratory, Sydney Children’s Hospital. Associated Investigator, Children’s Cancer Institute Australia. Senior Lecturer, School of Women’s and Children’s Health Faculty of Medicine, UNSW, Australia
Dr Alla Dolnikov’s project – using MYC inhibitors to potentiate CAR-T cell therapy for neuroblastoma, was one of two major research projects awarded $125,000 in funding by Neuroblastoma Australia in 2020.
The project is researching a new way to make CAR-T therapy more effective in treating neuroblastoma tumours by suppressing the MYC oncogene. Currently CAR-T therapy which is seen as a promising way of using the body’s own immune system to tackle cancer cells has not worked on neuroblastoma tumours. But the award-winning research looks like there could be a way of changing this.
